Forty-three post-docs, graduate, and undergraduate students representing twelve universities participated in the second annual Science of Information summer school held May 30 \u2013 June 1, 2012 at Stanford University. The two primary purposes of the school were to 1) orient students to current research and approaches to grand challenges in the areas of communications, knowledge extraction from data, and life sciences problems where information theory can provide insights, and 2) foster networking between the students such that they gained knowledge of their peers\u2019 projects and ideas. Eleven CSoI faculty, one post-doc, and one senior research scientist presented surveys and tutorials. Lectures with video/audio/slides are available below in their entirety.