Center for Science of Information
Center for Science of Information


National Science Foundation
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  • R. Claudio Aguilar

  • Associate Professor and Assistant Head
    Department of Biological Sciences
    Purdue University

    Professor Aguilar's research is focused on the study of protein trafficking and membrane transport in relation to the processes of cell polarity establishment (a feature that is key for animal development and crucial physiological functions such as synaptic transmission and immune response) and carcinogenic transformation.

    "In order to pursue my research goals, I routinely use genetic, biochemistry and cell biology techniques with yeast and mammalian cells. I study protein-protein interactions at molecular level by using bioinformatics, biochemical and genetic tools (like the tow-hybrid system) and we investigate the physiological relevance of these interactions by using functional assays, microscopy (of live and fixed cells) and genetic approaches."



    Keywords
    Cell (biology)
    Developmental biology
    Molecular biology

    Years Active

    2011 2012 2013 2014 2015 2016 2017 2018 2019
    Associated Resources

    • Journal Papers: Introduction to the analysis of the intracellular sorting information in protein sequences: From Molecular Biology to Artificial Neural Networks
    • Journal Papers: The Saccharomyces cerevisiae Na+ ATPase exporter ENa1 is a yeast epsin-specific endocytic cargo
    • Journal Papers: Crystallographic analysis of the ENTH domain from yeast epsin Ent2 that induces a cell division phenotype
    • Journal Papers: Artificial Neural Network for the Prediction of Tyrosine-Based Sorting Signal Recognition by Clathrin-Associated Adaptor Complexes
    • Journal Papers: The epsin protein family: coordinators of endocytosis and signaling
    • Journal Papers: Evolution of the membrane localization determinants within the epsin family of endocytic proteins
    • Journal Papers: Ubiquitination and the presence of a ST-motif is required for the endocytosis of the yeast ATPase ENa1
    • Journal Papers: Endocytosis and cell division
    • Journal Papers: Microfluidic based contactless dielectrophoretic device: Modeling and analysis
    • Video: Dr. Claudio Aguilar, Science of Information and Cell Biology
    • Video: Challenges in the Biology Front or How the Theory of Information Can Save Lives
    Associated Events

    • 2016 NSF Site Visit
    • 2015 NSF Site Visit
    • Science of Information for Life Sciences Data – Student and Postdoc Workshop
    • Thesis Defense - Kayal Madhivanan
    • Science of Information for Biological Data - Student Workshop
    • Information and Cell Biology in Health and Disease
    • 2011 Science of Information Summer School
    • Industrial Partnership Roundtable
    • Challenges in the Biology Front or How the Theory of Information Can Save Lives

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Made possible by grant NSF CCF-0939370